Marlow Industries was established as an independent private corporation in 1973 to offer industry and government a single-source capability for all aspects of thermoelectric technology, cooling, heating and power generation. In 2004, Marlow Industries was purchased by II-VI Incorporated. II-VI is a public company trading on the NASDAQ under the stock symbol IIVI.
The TEM thermocycler is a device used for PCR (Polymerase Chain Reaction) and other thermal cycling applications. This equipment utilizes thermoelectric cooling technology to provide precise temperature control in laboratory settings. The core function of a thermocycler is to facilitate the PCR reaction by periodically changing temperatures, which involves three main steps: high-temperature denaturation, annealing at a suitable temperature, and low-temperature extension, each requiring specific temperature conditions. Traditional PCR processes required manually transferring samples between water baths at different temperatures, a process that was time-consuming and prone to errors. However, with the invention and application of thermocyclers, this process has been automated, greatly improving the efficiency and accuracy of experiments.
II-VI Marlow's TEM thermocycler features a compact size (30x30x33mm), making it suitable for occasions that require miniaturization and precise temperature control. The design of such a thermocycler typically includes a temperature control module that automatically adjusts temperatures according to a preset program, thereby achieving precise control of the PCR reaction.
When selecting a thermocycler, several factors need to be considered, including the accuracy and uniformity of temperature, precision of temperature control, the relationship between sample and block temperatures, flexibility and design, reliability, durability and quality, as well as warranty and service support. These factors collectively determine the performance and applicability of the thermocycler, thereby affecting the efficiency and quality of laboratory research outcomes.
In summary, the TEM thermocycler is an indispensable tool in modern molecular biology research. It has greatly advanced the development and application of PCR technology through automation and precise temperature control.